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AKA-387
Icotrokinra Hydrochloride
Cat. No.
AKA-387
CAS No.
3049491-48-4
MF
C90H120N20O22S2.xHCl
MW
1898.17 (calculated as free base)
Icotrokinra Hydrochloride is a synthetic cyclic peptide composed of 13 amino acid residues and acts as a selective interleukin-23 receptor (IL-23R) antagonist.
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Technical Data
Description
Storage and Shipping
References
Product Name
Icotrokinra Hydrochloride
CAS No.
3049491-48-4
MF
C90H120N20O22S2.xHCl
MW
1898.17 (calculated as free base)
Specification
95.0%~105.0%
Research area
Immunology
Documents
Certificate of Analysis (COA), API specification sheet, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Description
Icotrokinra Hydrochloride is a synthetic cyclic peptide composed of 13 amino acid residues and acts as a selective interleukin-23 receptor (IL-23R) antagonist. Packing: 1kg/bag,5kg/bag Availability: In stock API Current Development Status: A3---Process Development / Scale-Up Reference: Aktin major API development processes: A1.Feasibility / Route Development A2.Laboratory Process Development A3.Process Development / Scale-Up A4.GMP Clinical Development A5.Commercial GMP Supply
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1].Fourie AM, Cheng X, Chang L, et al. JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans. Sci Rep. 2024;14:17515. doi:10.1038/s41598-024-67371-5.
[2].Fourie AM, Cheng X, Chang L, et al. JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans. Sci Rep. 2024;14:17515. doi:10.1038/s41598-024-67371-5.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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